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Galectin Therapeutics belapectin galectin 3 inhibitor
Belapectin Galectin 3 Inhibitor, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Class of considered drugs for treating MASH/MASLD.

Journal: International Journal of Molecular Sciences

Article Title: Current Therapeutic Landscape for Metabolic Dysfunction-Associated Steatohepatitis

doi: 10.3390/ijms26041778

Figure Lengend Snippet: Class of considered drugs for treating MASH/MASLD.

Article Snippet: , Galectin-3 inhibitor , Belapectin [ , ] , Inhibits galectin-3, targeting fibrosis and inflammation pathways , Large molecule galactoarabino-rhamnogalacturonan polysaccharide inhibitor derived from natural sources; prevents formation of oligomeric structures and lattice-like assemblies that are essential for activating pro-fibrotic signaling pathways, thereby halting fibrosis and reducing liver inflammation.

Techniques: Drug discovery, Control, Clinical Proteomics, Variant Assay, Expressing, Allele-specific Oligonucleotide, Activity Assay, Activation Assay, Derivative Assay, Protein-Protein interactions, Probiotics, Produced, Bacteria, Transplantation Assay

Drugs with ongoing or upcoming phase 3 and 4 clinical trials for NAFLD/NASH.

Journal: United European Gastroenterology Journal

Article Title: Therapeutic management of metabolic dysfunction associated steatotic liver disease

doi: 10.1002/ueg2.12525

Figure Lengend Snippet: Drugs with ongoing or upcoming phase 3 and 4 clinical trials for NAFLD/NASH.

Article Snippet: Belapectin , Galectin‐3 (Gal‐3) inhibitor , NAVIGATE (NCT04365868) , Patients with NASH cirrhosis and clinical signs of portal hypertension but without oesophageal varices at baseline , Evaluating the efficacy and safety of belapectin for the prevention of esophageal varices in NASH cirrhosis , 2020 , Phase 2b/3 , Galectin Therapeutics Inc..

Techniques: Clinical Proteomics, Control

Therapeutic targets under investigation for portal hypertension.

Journal: Frontiers in Medicine

Article Title: Current and investigational drugs in early clinical development for portal hypertension

doi: 10.3389/fmed.2022.974182

Figure Lengend Snippet: Therapeutic targets under investigation for portal hypertension.

Article Snippet: , Galectin-3 Inhibitors , Belapectin , Small clinical study. *ongoing RCT , .

Techniques: Biomarker Discovery, Clinical Proteomics